Click Here to return To Results

 

Cognitive Recovery Instead of Decline After Acute Encephalitis:A Prospective Follow Up Study JNNP 63:222-227, Hokkanen,L.&Launes,J., 1997 See this aricle in Pubmed Article Abstract In six of 11 cases the symptoms causing disability were mainly psychiatric.Five patients(two with HSVE)had a pronounced memory impairment together with other cognitive deficits,indicating dementia(frequency of 12.8%).In eight of the 11 testable cases cognitive performance had improved over the years,in two cases a decline was found and one patient with severe deficits showed no change.Intractable epilepsy was found in four of 12 cases.Cognitive decline had taken place already at the acute stage,and further deterioration was uncommon.Considerable improvement occurred in most patients during follow up.Also in patients with HSVE treated with acyclovir the cognitive recovery was substantial and of a magnitude not expected based on previous literature.Intractable epilepsy contributed to the cognitive deterioration in some cases.Affective disorders also had a surprisingly important role for the long term outcome.

Related Tags

(click to filter results - removes previous filter) cognition dementia encephalitis encephalitis,clinical picture and treatment of encephalitis,sequelae in herpes simplex encephalitis memory,impairment of prognosis psychological testing seizure seizure,intractable

Click Here to return To Results